Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats

Pulmonary arterial hypertension (PAH) is a progressive fatal disease with no cure. Inhibition of integrin-linked kinase (ILK) reverses experimental pulmonary hypertension (PH) in male mice, but its effect on severe experimental PH in either male or female animals is unknown. We examined effects of I...

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Veröffentlicht in:Pulm Circ
Hauptverfasser: Shen, Yuanjun, Goncharov, Dmitry A., Avolio, Theodore, Ray, Arnab, Okorie, Evelyn, DeLisser, Horace, Mora, Ana L., Vanderpool, Rebecca, Kudryashova, Tatiana V., Goncharova, Elena A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016388/
https://ncbi.nlm.nih.gov/pubmed/32110386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019898593
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