MiR-18a-downregulated RORA inhibits the proliferation and tumorigenesis of glioma using the TNF-α-mediated NF-κB signaling pathway

BACKGROUND: Glioma has a poor prognosis, and is the most common primary and lethal primary malignant tumor in the central nervous system. Retinoic acid receptor-related orphan receptor A (RORA) is a member of the ROR subfamily of orphan receptors and plays an anti-tumor role in several cancers. METH...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Jiang, Yang, Zhou, Jinpeng, Zhao, Junshuang, Hou, Dianqi, Zhang, Haiying, Li, Long, Zou, Dan, Hu, Jiangfeng, Zhang, Ye, Jing, Zhitao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016377/
https://ncbi.nlm.nih.gov/pubmed/32062354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102651
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