Prosaposin promotes the proliferation and tumorigenesis of glioma through toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway

BACKGROUND: As a neurotrophic factor, prosaposin (PSAP) can exert neuroprotective and neurotrophic effects. It is involved in the occurrence and development of prostate and breast cancer. However, there is no research about the role of PSAP in glioma. METHODS: The PSAP overexpressed or silenced glio...

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Foilsithe in:EBioMedicine
Main Authors: Jiang, Yang, Zhou, Jinpeng, Luo, Peng, Gao, Huiling, Ma, Yanju, Chen, Yin-Sheng, Li, Long, Zou, Dan, Zhang, Ye, Jing, Zhitao
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018
Ábhair:
Research paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286187/
https://ncbi.nlm.nih.gov/pubmed/30385233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.053
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