Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia

BACKGROUND: Glioma is the most common primary malignant tumor in the central nervous system with frequent hypoxia and angiogenesis. Limb-Bud and Heart (LBH) is a highly conserved transcription cofactor that participates in embryonic development and tumorigenesis. METHODS: The conditioned media from...

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Vydáno v:EBioMedicine
Hlavní autoři: Jiang, Yang, Zhou, Jinpeng, Zou, Dan, Hou, Dianqi, Zhang, Haiying, Zhao, Junshuang, Li, Long, Hu, Jiangfeng, Zhang, Ye, Jing, Zhitao
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838451/
https://ncbi.nlm.nih.gov/pubmed/31631037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.037
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