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Cutting antiparallel DNA strands in a single active site
A single enzyme active site that catalyzes multiple reactions is a well-established biochemical theme, but how one nuclease site cleaves both DNA strands of a double helix has not been well understood. In analyzing site-specific DNA cleavage by the mammalian RAG1-RAG2 recombinase, which initiates V(...
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| Pubblicato in: | Nat Struct Mol Biol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7015813/ https://ncbi.nlm.nih.gov/pubmed/32015552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0363-2 |
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