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DNA fragmentation during apoptosis is caused by frequent single-strand cuts.

One of the hallmarks of apoptosis is the digestion of genomic DNA by an endonuclease, generating a ladder of small fragments of double-stranded DNA. We have examined the nature of the DNA breaks produced in mouse thymocytes triggered to undergo apoptosis by steroids or by stimulation of the T cell r...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Peitsch, M C, Müller, C, Tschopp, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC310051/
https://ncbi.nlm.nih.gov/pubmed/8414975
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