Leptin Controls Glutamatergic Synaptogenesis and NMDA-Receptor Trafficking via Fyn Kinase Regulation of NR2B

Activation of the leptin receptor, LepRb, by the adipocytokine/neurotrophic factor leptin in the central nervous system has procognitive and antidepressive effects. Leptin has been shown to increase glutamatergic synaptogenesis in multiple brain regions. In contrast, mice that have a mutation in the...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Bland, Tyler, Zhu, Mingyan, Dillon, Crystal, Sahin, Gulcan Semra, Rodriguez-Llamas, Jose Luis, Appleyard, Suzanne M, Wayman, Gary A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015580/
https://ncbi.nlm.nih.gov/pubmed/31840160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqz030
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