The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

Ferroptosis, a form of regulated cell death caused by lipid peroxidation, was recently identified as a natural tumor suppression mechanism. Here, we show that ionizing radiation (IR) induces ferroptosis in cancer cells. Mechanistically, IR induces not only reactive oxygen species (ROS) but also the...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Lei, Guang, Zhang, Yilei, Koppula, Pranavi, Liu, Xiaoguang, Zhang, Jie, Lin, Steven H., Ajani, Jaffer A., Xiao, Qin, Liao, Zhongxing, Wang, Hui, Gan, Boyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015061/
https://ncbi.nlm.nih.gov/pubmed/31949285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0263-3
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