A toxicogenomic approach for the risk assessment of the food contaminant acetamide

Acetamide (CAS 60-35-5) is detected in common foods. Chronic rodent bioassays led to its classification as a group 2B possible human carcinogen due to the induction of liver tumors in rats. We used a toxicogenomics approach in Wistar rats gavaged daily for 7 or 28 days at doses of 300 to 1500 mg/kg/...

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Bibliografske podrobnosti
izdano v:Toxicol Appl Pharmacol
Main Authors: Nault, Rance, Bals, Bryan, Teymouri, Farzaneh, Black, Michael B., Andersen, Melvin E., McMullen, Patrick D., Krishnan, Seetha, Kuravadi, Nagesh, Paul, Neetha, Kumar, Santhosh, Kannan, Kamala, Jayachandra, K.C., Alagappan, Lakshmanan, Patel, Bhavesh Dhirajlal, Bogen, Kenneth T., Gollapudi, Bhaskar B., Klaunig, James E., Zacharewski, Tim R., Bringi, Venkataraman
Format: Artigo
Jezik:Inglês
Izdano: Academic Press 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014822/
https://ncbi.nlm.nih.gov/pubmed/31881176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2019.114872
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