Comparative transcriptomic analysis reveals the significant pleiotropic regulatory effects of LmbU on lincomycin biosynthesis

BACKGROUND: Lincomycin, produced by Streptomyces lincolnensis, is a lincosamide antibiotic and widely used for the treatment of the infective diseases caused by Gram-positive bacteria. The mechanisms of lincomycin biosynthesis have been deeply explored in recent years. However, the regulatory effect...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Lin, Chun-Yan, Pang, Ai-Ping, Zhang, Yue, Qiao, Jianjun, Zhao, Guang-Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014725/
https://ncbi.nlm.nih.gov/pubmed/32050973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01298-0
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