The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis

Lincomycin A is a clinically important antimicrobial agent produced by Streptomyces lincolnensis. In this study, a new regulator designated LmbU (GenBank accession no. ABX00623.1) was identified and characterized to regulate lincomycin biosynthesis in S. lincolnensis wild-type strain NRRL 2936. Both...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Hou, Bingbing, Lin, Yanwei, Wu, Haizhen, Guo, Meijin, Petkovic, Hrvoje, Tao, Liyuan, Zhu, Xiaoyu, Ye, Jiang, Zhang, Huizhan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738732/
https://ncbi.nlm.nih.gov/pubmed/29038257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00447-17
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