LmbU, a Cluster-Situated Regulator for Lincomycin, Consists of a DNA-Binding Domain, an Auto-Inhibitory Domain, and Forms Homodimer

Few studies were reported about the regulatory mechanism of lincomycin biosynthesis since it was found in 1962. Although we have proved that a cluster-situated regulator (CSR) LmbU (GenBank Accession No. ABX00623.1) positively modulates lincomycin biosynthesis in Streptomyces lincolnensis NRRL 2936,...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Hou, Bingbing, Zhu, Xiaoyu, Kang, Yajing, Wang, Ruida, Wu, Haizhen, Ye, Jiang, Zhang, Huizhan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510168/
https://ncbi.nlm.nih.gov/pubmed/31130942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00989
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