Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtype

BACKGROUND: The molecular mechanisms underlying the association between increased adiposity and aggressive breast cancer phenotypes remain unclear, but likely involve the adipokines, leptin (LEP) and adiponectin (ADIPOQ), and their receptors (LEPR, ADIPOR1, ADIPOR2). METHODS: We used immunohistochem...

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Publicado en:Breast Cancer Res
Autores principales: Llanos, Adana A. M., Lin, Yong, Chen, Wenjin, Yao, Song, Norin, Jorden, Chekmareva, Marina A., Omene, Coral, Cong, Lei, Omilian, Angela R., Khoury, Thaer, Hong, Chi-Chen, Ganesan, Shridar, Foran, David J., Higgins, Michael, Ambrosone, Christine B., Bandera, Elisa V., Demissie, Kitaw
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014630/
https://ncbi.nlm.nih.gov/pubmed/32046756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-1256-3
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