Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtype

BACKGROUND: The molecular mechanisms underlying the association between increased adiposity and aggressive breast cancer phenotypes remain unclear, but likely involve the adipokines, leptin (LEP) and adiponectin (ADIPOQ), and their receptors (LEPR, ADIPOR1, ADIPOR2). METHODS: We used immunohistochem...

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Gepubliceerd in:Breast Cancer Res
Hoofdauteurs: Llanos, Adana A. M., Lin, Yong, Chen, Wenjin, Yao, Song, Norin, Jorden, Chekmareva, Marina A., Omene, Coral, Cong, Lei, Omilian, Angela R., Khoury, Thaer, Hong, Chi-Chen, Ganesan, Shridar, Foran, David J., Higgins, Michael, Ambrosone, Christine B., Bandera, Elisa V., Demissie, Kitaw
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014630/
https://ncbi.nlm.nih.gov/pubmed/32046756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-1256-3
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