Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtype

BACKGROUND: The molecular mechanisms underlying the association between increased adiposity and aggressive breast cancer phenotypes remain unclear, but likely involve the adipokines, leptin (LEP) and adiponectin (ADIPOQ), and their receptors (LEPR, ADIPOR1, ADIPOR2). METHODS: We used immunohistochem...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Llanos, Adana A. M., Lin, Yong, Chen, Wenjin, Yao, Song, Norin, Jorden, Chekmareva, Marina A., Omene, Coral, Cong, Lei, Omilian, Angela R., Khoury, Thaer, Hong, Chi-Chen, Ganesan, Shridar, Foran, David J., Higgins, Michael, Ambrosone, Christine B., Bandera, Elisa V., Demissie, Kitaw
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014630/
https://ncbi.nlm.nih.gov/pubmed/32046756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-1256-3
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