Presenilin1 exerts antiproliferative effects by repressing the Wnt/β-catenin pathway in glioblastoma

BACKGROUND: Glioblastoma and Alzheimer’s disease (AD) are the most common and devastating diseases in the central nervous system. The dysfunction of Presenilin1 is the main reason for AD pathogenesis. However, the molecular function of Presenilin1 and its relative mechanism in glioblastoma remain un...

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Spremljeno u:
Bibliografski detalji
Izdano u:Cell Commun Signal
Glavni autori: Yang, Wei, Wu, Peng-fei, Ma, Jian-xing, Liao, Mao-jun, Xu, Lun-shan, Xu, Min-hui, Yi, Liang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Methodology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014622/
https://ncbi.nlm.nih.gov/pubmed/32046730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0501-9
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