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Presenilin1 exerts antiproliferative effects by repressing the Wnt/β-catenin pathway in glioblastoma

BACKGROUND: Glioblastoma and Alzheimer’s disease (AD) are the most common and devastating diseases in the central nervous system. The dysfunction of Presenilin1 is the main reason for AD pathogenesis. However, the molecular function of Presenilin1 and its relative mechanism in glioblastoma remain un...

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Detalles Bibliográficos
Publicado en:Cell Commun Signal
Main Authors: Yang, Wei, Wu, Peng-fei, Ma, Jian-xing, Liao, Mao-jun, Xu, Lun-shan, Xu, Min-hui, Yi, Liang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014622/
https://ncbi.nlm.nih.gov/pubmed/32046730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0501-9
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