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PI3Kβ inhibitor AZD6482 exerts antiproliferative activity and induces apoptosis in human glioblastoma cells

Glioblastoma is the most common type of primary brain tumour in adults, and its pathogenesis is particularly complicated. Among the many possible mechanisms underlying its pathogenesis, hyperactivation of the PI3K/Akt pathway is essential to the occurrence and development of glioma through the loss...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Xu, Peng-Fei, Yang, Ji-An, Liu, Jun-Hui, Yang, Xue, Liao, Jian-Ming, Yuan, Fan-En, Liu, Bao-Hui, Chen, Qian-Xue
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278584/
https://ncbi.nlm.nih.gov/pubmed/30542720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6845
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