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PI3Kβ inhibitor AZD6482 exerts antiproliferative activity and induces apoptosis in human glioblastoma cells

Glioblastoma is the most common type of primary brain tumour in adults, and its pathogenesis is particularly complicated. Among the many possible mechanisms underlying its pathogenesis, hyperactivation of the PI3K/Akt pathway is essential to the occurrence and development of glioma through the loss...

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Bibliografische gegevens
Gepubliceerd in:Oncol Rep
Hoofdauteurs: Xu, Peng-Fei, Yang, Ji-An, Liu, Jun-Hui, Yang, Xue, Liao, Jian-Ming, Yuan, Fan-En, Liu, Bao-Hui, Chen, Qian-Xue
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278584/
https://ncbi.nlm.nih.gov/pubmed/30542720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6845
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