TGX-221 inhibits proliferation and induces apoptosis in human glioblastoma cells

Glioblastoma is the most common type of primary brain tumor in adults, with high mortality and morbidity rates. More effective therapeutic strategies are imperative. Previous studies have shown that the known p110-β-selective inhibitor TGX-221 blocks the activation of PKB/Akt in PTEN-deficient cells...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Yang, Xue, Yang, Ji-An, Liu, Bao-Hui, Liao, Jian-Ming, Yuan, Fan-En, Tan, Yin-Qiu, Chen, Qian-Xue
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780035/
https://ncbi.nlm.nih.gov/pubmed/29048665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5991
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