Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221

Bufalin, a major component of the Chinese medicine ChanSu, which is prepared from the skin and parotid venom glands of toads, has shown cytotoxicity in several malignant tumors. Here, we reported that bufalin inhibited proliferation and induced mitochondria-dependent apoptosis in U-2OS and Saos-2 os...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Zhang, Jianjun, Sha, Jingjing, Zhou, Yan, Han, Kun, Wang, Yaling, Su, Yang, Yin, Xiuyi, Hu, Haiyan, Yao, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198087/
https://ncbi.nlm.nih.gov/pubmed/28074104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7319464
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