Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221

Bufalin, a major component of the Chinese medicine ChanSu, which is prepared from the skin and parotid venom glands of toads, has shown cytotoxicity in several malignant tumors. Here, we reported that bufalin inhibited proliferation and induced mitochondria-dependent apoptosis in U-2OS and Saos-2 os...

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Bibliografiske detaljer
Udgivet i:Evid Based Complement Alternat Med
Main Authors: Zhang, Jianjun, Sha, Jingjing, Zhou, Yan, Han, Kun, Wang, Yaling, Su, Yang, Yin, Xiuyi, Hu, Haiyan, Yao, Yang
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198087/
https://ncbi.nlm.nih.gov/pubmed/28074104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7319464
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