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Components from the Human c-myb Transcriptional Regulation System Reactivate Epigenetically Repressed Transgenes
A persistent challenge for mammalian cell engineering is the undesirable epigenetic silencing of transgenes. Foreign DNA can be incorporated into closed chromatin before and after it has been integrated into a host cell’s genome. To identify elements that mitigate epigenetic silencing, we tested com...
Gardado en:
| Publicado en: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7014047/ https://ncbi.nlm.nih.gov/pubmed/31947658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020530 |
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