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D-type cyclins repress transcriptional activation by the v-Myb but not the c-Myb DNA-binding domain.
The v-Myb DNA-binding domain differs from that of c-Myb mainly by deletion of the first of three repeats. This truncation correlates with efficient oncogenic transformation and a decrease in DNA-binding activity. Here we demonstrate that the D-type cyclins, cyclin D1 and D2 in particular, specifical...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1998
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170376/ https://ncbi.nlm.nih.gov/pubmed/9427759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.1.255 |
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