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Identification of Key Coagulation Activity Determining Elements in Canine Factor VIII

It is well known that canine factor VIII (cFVIII) has a higher specific activity than does human FVIII (hFVIII), and it has been previously demonstrated that cFVIII light chain is able to enhance hFVIII activity. The goal of this study was to first determine which amino acids in cFVIII light chain w...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Firrman, Jenni, Wang, Qizhao, Wu, Wenman, Dong, Biao, Cao, Wenjing, Moore, Andrea Rossi, Roberts, Sean, Konkle, Barbara A., Miao, Carol, Liu, LinShu, Li, Dong, Xiao, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013134/
https://ncbi.nlm.nih.gov/pubmed/32071925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.12.019
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