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Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors
Following assembly, the anthrax protective antigen (PA) forms an oligomeric translocon that unfolds and translocates either its lethal factor (LF) or edema factor (EF) into the host cell. Here, we report the cryo-EM structures of heptameric PA channels with partially unfolded LF and EF at 4.6 and 3....
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7012834/ https://ncbi.nlm.nih.gov/pubmed/32047164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14658-6 |
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