Načítá se...

Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors

Following assembly, the anthrax protective antigen (PA) forms an oligomeric translocon that unfolds and translocates either its lethal factor (LF) or edema factor (EF) into the host cell. Here, we report the cryo-EM structures of heptameric PA channels with partially unfolded LF and EF at 4.6 and 3....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Hardenbrook, Nathan J., Liu, Shiheng, Zhou, Kang, Ghosal, Koyel, Zhou, Z. Hong, Krantz, Bryan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012834/
https://ncbi.nlm.nih.gov/pubmed/32047164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14658-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!