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Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors
Following assembly, the anthrax protective antigen (PA) forms an oligomeric translocon that unfolds and translocates either its lethal factor (LF) or edema factor (EF) into the host cell. Here, we report the cryo-EM structures of heptameric PA channels with partially unfolded LF and EF at 4.6 and 3....
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7012834/ https://ncbi.nlm.nih.gov/pubmed/32047164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14658-6 |
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