RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates

Increasing Neisseria gonorrhoeae resistance to ceftriaxone, the last antibiotic recommended for empiric gonorrhea treatment, poses an urgent public health threat. However, the genetic basis of reduced susceptibility to ceftriaxone is not completely understood: while most ceftriaxone resistance in cl...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Palace, Samantha G, Wang, Yi, Rubin, Daniel HF, Welsh, Michael A, Mortimer, Tatum D, Cole, Kevin, Eyre, David W, Walker, Suzanne, Grad, Yonatan H
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Microbiology and Infectious Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012608/
https://ncbi.nlm.nih.gov/pubmed/32011233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51407
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