RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates

Increasing Neisseria gonorrhoeae resistance to ceftriaxone, the last antibiotic recommended for empiric gonorrhea treatment, poses an urgent public health threat. However, the genetic basis of reduced susceptibility to ceftriaxone is not completely understood: while most ceftriaxone resistance in cl...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Palace, Samantha G, Wang, Yi, Rubin, Daniel HF, Welsh, Michael A, Mortimer, Tatum D, Cole, Kevin, Eyre, David W, Walker, Suzanne, Grad, Yonatan H
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2020
Sujets:
Microbiology and Infectious Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012608/
https://ncbi.nlm.nih.gov/pubmed/32011233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51407
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