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Tumor mutational burden as a predictive biomarker for checkpoint inhibitor immunotherapy

Immune checkpoint inhibitor (ICI) therapies can achieve meaningful tumor responses in a subset of patients with most types of cancer that have been investigated. However, the majority of patients treated with these drugs do not experience any clinical benefit. Because not all patients benefit from I...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Lee, Mark, Samstein, Robert M., Valero, Cristina, Chan, Timothy A., Morris, Luc G.T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012182/
https://ncbi.nlm.nih.gov/pubmed/31361563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1631136
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