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The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy

Checkpoint inhibitor-based immunotherapies that target cytotoxic T lymphocyte antigen 4 (CTLA4) or the programmed cell death 1 (PD1) pathway have achieved impressive success in the treatment of different cancer types. Yet, only a subset of patients derive clinical benefit. It is thus critical to und...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Havel, Jonathan J., Chowell, Diego, Chan, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705396/
https://ncbi.nlm.nih.gov/pubmed/30755690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41568-019-0116-x
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