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Enantioselective synthesis of P-chiral tertiary phosphine oxides with an ethynyl group via Cu(i)-catalyzed azide–alkyne cycloaddition

We report the highly enantioselective synthesis of P-chiral tertiary phosphine oxides featuring an ethynyl group via Cu(i)-catalyzed azide–alkyne cycloaddition. Newly developed chiral pyridinebisoxazolines (PYBOX) bearing a bulky C4 shielding group play an important role in achieving excellent enant...

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Vydáno v:Chem Sci
Hlavní autoři: Zhu, Ren-Yi, Chen, Long, Hu, Xiao-Si, Zhou, Feng, Zhou, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012078/
https://ncbi.nlm.nih.gov/pubmed/32110361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04938j
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