Benzimidazole derivatives endowed with potent antileishmanial activity

Two sets of benzimidazole derivatives were synthesised and tested in vitro for activity against promastigotes of Leishmania tropica and L. infantum. Most of the tested compounds resulted active against both Leishmania species, with IC(50) values in the low micromolar/sub-micromolar range. Among the...

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Publicado en:J Enzyme Inhib Med Chem
Autores principales: Tonelli, Michele, Gabriele, Elena, Piazza, Francesca, Basilico, Nicoletta, Parapini, Silvia, Tasso, Bruno, Loddo, Roberta, Sparatore, Fabio, Sparatore, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011974/
https://ncbi.nlm.nih.gov/pubmed/29233048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1410480
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