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Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles

Respiratory syncytial virus (RSV) has been identified as a main cause of hospitalisation in infants and children. To date, the current therapeutic arsenal is limited to ribavirin and palivizumab with variable efficacy. In this work, starting from a number of in-house series of previously described a...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Cichero, Elena, Tonelli, Michele, Novelli, Federica, Tasso, Bruno, Delogu, Ilenia, Loddo, Roberta, Bruno, Olga, Fossa, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021036/
https://ncbi.nlm.nih.gov/pubmed/28276287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1256881
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