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A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways
Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization. We created transgenic Drosophila lines expressing the catalytic subunit CDTa to investig...
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| Publicado no: | iScience |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7011083/ https://ncbi.nlm.nih.gov/pubmed/32058973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100865 |
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