A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways

Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization. We created transgenic Drosophila lines expressing the catalytic subunit CDTa to investig...

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Detaylı Bibliyografya
Yayımlandı:iScience
Asıl Yazarlar: Schwartz, Ruth, Guichard, Annabel, Franc, Nathalie C., Roy, Sitara, Bier, Ethan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011083/
https://ncbi.nlm.nih.gov/pubmed/32058973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100865
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