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The common message of constraint-based optimization approaches: overflow metabolism is caused by two growth-limiting constraints
Living cells can express different metabolic pathways that support growth. The criteria that determine which pathways are selected in which environment remain unclear. One recurrent selection is overflow metabolism: the simultaneous usage of an ATP-efficient and -inefficient pathway, shown for examp...
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| Published in: | Cell Mol Life Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer International Publishing
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7010627/ https://ncbi.nlm.nih.gov/pubmed/31758233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03380-2 |
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