Loss of tissue-nonspecific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

Sepsis is a host response to systemic inflammation and infection that may lead to multi-organ dysfunction and eventual death. While acute brain dysfunction is common among all sepsis patients, chronic neurological impairment is prevalent among sepsis survivors. The brain microvasculature has emerged...

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Foilsithe in:Brain Behav Immun
Main Authors: Nwafor, Divine C., Chakraborty, Sreeparna, Brichacek, Allison L., Jun, Sujung, Gambill, Catheryne A., Wang, Wei, Engler-Chiurazzi, Elizabeth B., Dakhlallah, Duaa, Pinkerton, Anthony B., Millán, José Luis, Benkovic, Stanley A., Brown, Candice M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010562/
https://ncbi.nlm.nih.gov/pubmed/31778743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2019.11.016
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