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ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue

Mitochondria play a central role in the function of brown adipocytes (BAs). Although mitochondrial biogenesis, which is indispensable for thermogenesis, is regulated by coordination between nuclear DNA transcription and mitochondrial DNA transcription, the molecular mechanisms of mitochondrial devel...

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Bibliographic Details
Published in:Life Sci Alliance
Main Authors: Kato, Hironori, Okabe, Kohki, Miyake, Masato, Hattori, Kazuki, Fukaya, Tomohiro, Tanimoto, Kousuke, Beini, Shi, Mizuguchi, Mariko, Torii, Satoru, Arakawa, Satoko, Ono, Masaya, Saito, Yusuke, Sugiyama, Takashi, Funatsu, Takashi, Sato, Katsuaki, Shimizu, Shigeomi, Oyadomari, Seiichi, Ichijo, Hidenori, Kadowaki, Hisae, Nishitoh, Hideki
Format: Artigo
Language:Inglês
Published: Life Science Alliance LLC 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010021/
https://ncbi.nlm.nih.gov/pubmed/32029570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900576
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