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A Highly Productive, One-Pot Cell-Free Protein Synthesis Platform Based on Genomically Recoded Escherichia coli

The site-specific incorporation of non-canonical amino acids (ncAAs) into proteins via amber suppression provides access to novel protein properties, structures, and functions. Historically, poor protein expression yields resulting from release factor 1 (RF1) competition has limited this technology....

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Publicat a:Cell Chem Biol
Autors principals: Des Soye, Benjamin J., Gerbasi, Vincent R., Thomas, Paul M., Kelleher, Neil L., Jewett, Michael C.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008506/
https://ncbi.nlm.nih.gov/pubmed/31706984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.10.008
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