Hypoxia Induces Growth Differentiation Factor 15 to Promote the Metastasis of Colorectal Cancer via PERK-eIF2α Signaling

Hypoxia plays an essential role in orchestrating Epithelial-mesenchymal transition and promoting metastasis of colorectal cancer. However, the underlying mechanisms are still not well elucidated. Here, we present that hypoxic exposure causes endoplasmic reticulum stress and activates the unfolded pr...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zheng, Hongtu, Wu, Yuchen, Guo, Tianan, Liu, Fangqi, Xu, Ye, Cai, Sanjun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008299/
https://ncbi.nlm.nih.gov/pubmed/32076610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5958272
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