Salubrinal protects against tunicamycin and hypoxia induced cardiomyocyte apoptosis via the PERK-eIF2α signaling pathway

OBJECTIVES: This study examined the protective effect of salubrinal and the mechanism underlying this protection against tunicamycin (TM)- and hypoxia-induced apoptosis in rat cardiomyocytes. METHODS: Neonatal rat cardiomyocytes were cultured from the ventricles of 1-day-old Wistar rats. Cells were...

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Detalhes bibliográficos
Main Authors: Liu, Chun-Lei, Li, Xin, Hu, Guo-Liang, Li, Rui-Jun, He, Yun-Yun, Zhong, Wu, Li, Song, He, Kun-Lun, Wang, Li-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Science Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470025/
https://ncbi.nlm.nih.gov/pubmed/23097656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3724/SP.J.1263.2012.02292
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