Osteoporosis regulation by salubrinal through eIF2α mediated differentiation of osteoclast and osteoblast

Nuclear factor-κB (NF-κB) ligand (RANKL) was shown to induce osteoclast differentiation by increasing the expression of c-Fos, NFATc1 and TRAP. Salubrinal treatment to bone marrow macrophage (BMM) cells, however, significantly blocked NFATc1 expression and osteoclast differentiation by RANKL. Overex...

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Detalhes bibliográficos
Main Authors: He, Long, Lee, Junwon, Jang, Jae Hyuk, Sakchaisri, Krisada, Hwang, Joonsung, Cha-Molstad, Hyun Joo, Kim, Kyung A, Ryoo, In Ja, Lee, Hee Gu, Kim, Sun Ok, Soung, Nak Kyun, Lee, Kyung Sang, Kwon, Yong Tae, Erikson, Raymond Leo, Ahn, Jong Seog, Kim, Bo Yeon
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593652/
https://ncbi.nlm.nih.gov/pubmed/23178987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.11.015
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