STK295900, a Dual Inhibitor of Topoisomerase 1 and 2, Induces G(2) Arrest in the Absence of DNA Damage

STK295900, a small synthetic molecule belonging to a class of symmetric bibenzimidazoles, exhibits antiproliferative activity against various human cancer cell lines from different origins. Examining the effect of STK295900 in HeLa cells indicates that it induces G(2) phase arrest without invoking D...

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Detalhes bibliográficos
Main Authors: Kim, Sun-Ok, Sakchaisri, Krisada, N. R., Thimmegowda, Soung, Nak Kyun, Jang, Jae-Hyuk, Kim, Young Sang, Lee, Kyung Sang, Kwon, Yong Tae, Asami, Yukihiro, Ahn, Jong Seog, Erikson, Raymond Leo, Kim, Bo Yeon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551932/
https://ncbi.nlm.nih.gov/pubmed/23349762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053908
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