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Neuropeptide bombesin receptor activation stimulates growth of lung cancer cells through HER3 with a MAPK-dependent mechanism.
Despite recent advances in treatment of non-small cell lung cancer(NSCLC), prognosis still remains poor and new therapeutic approaches are needed. Studies demonstrate the importance of the EGFR/HER-receptor family in NSCLC growth, as well as that of other tumors. Recently, HER3 is receiving increase...
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| Publicado no: | Biochim Biophys Acta Mol Cell Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7008087/ https://ncbi.nlm.nih.gov/pubmed/31862538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2019.118625 |
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