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Bombesin receptor subtype-3 agonists stimulate the growth of lung cancer cells and increase EGF receptor tyrosine phosphorylation

The effects of bombesin receptor subtype-3 (BRS-3) agonists were investigated on lung cancer cells. The BRS-3 agonist (DTyr(6), βAla(11), Phe(13), Nle(14))bombesin(6-14) (BA1), but not gastrin releasing peptide (GRP) or neuromedin B (NMB) increased significantly the clonal growth of NCI-H1299 cells...

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Bibliografiske detaljer
Main Authors: Moody, Terry W., Sancho, Veronica, Florio, Alessia di, Nuche-Berenguer, Bernardo, Mantey, Samuel, Jensen, Robert T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152616/
https://ncbi.nlm.nih.gov/pubmed/21712056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.06.011
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