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Comparative Pharmacology of Bombesin Receptor Subtype-3, Nonpeptide Agonist MK-5046, a Universal Peptide Agonist, and Peptide Antagonist Bantag-1 for Human Bombesin Receptors

Bombesin-receptor-subtype-3 (BRS-3) is an orphan G-protein-coupled receptor of the bombesin (Bn) family whose natural ligand is unknown and which does not bind any natural Bn-peptide with high affinity. It is present in the central nervous system, peripheral tissues, and tumors; however, its role in...

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Autori principali: Moreno, Paola, Mantey, Samuel A., Nuche-Berenguer, Bernardo, Reitman, Marc L., González, Nieves, Coy, David H., Jensen, Robert T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781414/
https://ncbi.nlm.nih.gov/pubmed/23892571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.206896
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