Impact of TCR diversity on the development of transplanted or chemically induced tumors

Burnet postulated that the diversity of T-cell receptors (TCRs) allows T cells to protect against the development of cancers that display antigens with a similar, seemingly endless diversity. To test this hypothesis, we developed a strategy in which a single breeding pair of mice gives rise to four...

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Bibliografske podrobnosti
izdano v:Cancer Immunol Res
Main Authors: Schreiber, Karin, Karrison, Theodore G., Wolf, Steven P., Kiyotani, Kazuma, Steiner, Madeline, Littmann, Eric R., Pamer, Eric G., Kammertoens, Thomas, Schreiber, Hans, Leisegang, Matthias
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007920/
https://ncbi.nlm.nih.gov/pubmed/31831634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0567
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