Clinical implications of intratumor heterogeneity: challenges and opportunities

In this review, we highlight the role of intratumoral heterogeneity, focusing on the clinical and biological ramifications this phenomenon poses. Intratumoral heterogeneity arises through complex genetic, epigenetic, and protein modifications that drive phenotypic selection in response to environmen...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Mol Med (Berl)
Main Authors: Ramón y Cajal, Santiago, Sesé, Marta, Capdevila, Claudia, Aasen, Trond, De Mattos-Arruda, Leticia, Diaz-Cano, Salvador J., Hernández-Losa, Javier, Castellví, Josep
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007907/
https://ncbi.nlm.nih.gov/pubmed/31970428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01874-2
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