Clinical implications of intratumor heterogeneity: challenges and opportunities

In this review, we highlight the role of intratumoral heterogeneity, focusing on the clinical and biological ramifications this phenomenon poses. Intratumoral heterogeneity arises through complex genetic, epigenetic, and protein modifications that drive phenotypic selection in response to environmen...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Mol Med (Berl)
Auteurs principaux: Ramón y Cajal, Santiago, Sesé, Marta, Capdevila, Claudia, Aasen, Trond, De Mattos-Arruda, Leticia, Diaz-Cano, Salvador J., Hernández-Losa, Javier, Castellví, Josep
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2020
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007907/
https://ncbi.nlm.nih.gov/pubmed/31970428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01874-2
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