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Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo

Breast cancer is the most prevalent malignancy in women and there is an urgent need for new therapeutic drugs targeting aggressive and metastatic subtypes, such as hormone-refractory triple-negative breast cancer (TNBC). Control of protein synthesis is vital to cell growth and tumour progression and...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Sesé, Marta, Fuentes, Pedro, Esteve-Codina, Anna, Béjar, Eva, McGrail, Kimberley, Thomas, George, Aasen, Trond, Ramón y Cajal, Santiago
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777738/
https://ncbi.nlm.nih.gov/pubmed/29383126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23145
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