ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells

Metastasis, the spread of malignant cells from a primary tumour to distant sites, causes 90% of cancer-related deaths. The integrin ITGB3 has been previously described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. We have now uncovered essential...

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Udgivet i:Nat Commun
Main Authors: Fuentes, Pedro, Sesé, Marta, Guijarro, Pedro J., Emperador, Marta, Sánchez-Redondo, Sara, Peinado, Héctor, Hümmer, Stefan, Ramón y. Cajal, Santiago
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450082/
https://ncbi.nlm.nih.gov/pubmed/32848136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18081-9
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