Chargement en cours...

Thalamostriatal degeneration contributes to dystonia and cholinergic interneuron dysfunction in a mouse model of Huntington’s disease

Huntington’s disease (HD) is an autosomal dominant trinucleotide repeat disorder characterized by choreiform movements, dystonia and striatal neuronal loss. Amongst multiple cellular processes, abnormal neurotransmitter signalling and decreased trophic support from glutamatergic cortical afferents a...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Crevier-Sorbo, Gabriel, Rymar, Vladimir V., Crevier-Sorbo, Raphael, Sadikot, Abbas F.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007676/
https://ncbi.nlm.nih.gov/pubmed/32033588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-0878-0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!